Fabrication of rare-earth-doped LaOCl nanophosphors by using spray dryer

Fabrication of hydrophobic drug nanoparticles using a microfluidic spray dryer

We present a technique for fabricating hydrophobic drug nanoparticles using a microfluidic spray dryer. The nanoparticles are formed by evaporative precipitation of the spray in air at room temperature. Using danazol as a model drug, amorphous nanoparticles are yielded with narrow size distribution, 20-60 nm in diameter. As the device geometry allows us to inject two separate solvent streams, t...

Sol-Gel Fabrication of Rare-Earth Doped Photonic Components

The use of sol-gel to fabricate silica-on-silicon waveguides, and particularly erbium-doped waveguide amplifiers, is reviewed. In particular, efforts to use sol-gel to improve molecular homogeneity in heavily Er-doped silica-based films is discussed. A variety of material studies carried out to investigate the gain limitations found in these materials is then presented. These include x-ray diff...

Laser action in strongly scattering rare-earth-metal-doped dielectric nanophosphors

We report continuous-wave laser action in two oxide nanopowders doped with Ce and Pr ions. To our knowledge, these are the first observations of stimulated emission from electrically pumped random media in which scattering and distributed feedback scale lengths are much shorter than a wavelength. The continuous nature of the laser emission in small volumes ~on the order of a cubic wavelength! o...

Sensing Using Rare-Earth-Doped Upconversion Nanoparticles

Optical sensing plays an important role in theranostics due to its capability to detect hint biochemical entities or molecular targets as well as to precisely monitor specific fundamental psychological processes. Rare-earth (RE) doped upconversion nanoparticles (UCNPs) are promising for these endeavors due to their unique frequency converting capability; they emit efficient and sharp visible or...

Title Early development drug formulation on a chip: Fabrication of nanoparticles using a microfluidic spray dryer